Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus (SARS-CoV-2). The disease causes mild to severe symptoms, mainly respiratory, some patients can develop pneumonia, severe acute respiratory syndrome, kidney failure and even death. Any patient can develop mild to severe illness, but old age and severe underlying medical conditions like chronic lung disease, diabetes, obesity, ect. seem to be higher risk factors for developing more serious complications from COVID-19. There is no specific treatment for COVID-19. However, many of the symptoms can be treated according to the patient’s clinical condition. Adiantum capillus-veneris (Maidenhair fern) is a medicinal herb of the family Pteridaceae. The plant extract showed potential efficacy as ancient physicians used it for curing different diseases. In modern medicine, the plant was proven to possess pharmacological efficacy to treat many symptoms similar to that caused by COVID-19 and underlying medical conditions. Therefore, this ongoing study is done to examine possible effectiveness of modern therapeutic application of this plant extract-based drug to treat symptoms of patients with COVID-19.