SARS-CoV-2 host cell entry might involve Beta adrenergic receptors

Coronavirus disease 2019 (COVID-19) is caused by Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. SARS-CoV-2 enters the host cell by binding its spike protein with the angiotensin-converting enzyme 2 (ACE2) receptor. Cluster of differentiation 147 (CD147) also known as Basigin or extracellular matrix metalloproteinase inducer (EMMPRIN), has been proposed as another host cell receptor that might be involved in SARS-CoV-2 cellular entry . Any other host cell receptors that exist for SARS-CoV-2 is not known at present. I suggest that the Beta adrenergic receptor might be involved in the SARS-CoV-2 cell entry, and act as a co-receptor by its interaction via surface vimentin to the ACE2 receptor and by forming a complex with CD147.
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